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data-appid="panel" data-state="false"> <div class="igiokeaw4ag8" id="layout_20040304_style" class="hide"> </div> <div id="igiokeaw4ag8" class="appMask"></div> <div id="igiokeaw4ag8" class="appContent"> <div id="igiokeaw4ag8" class="phx-panel-wrap" data-showtitle="yes" data-isad="no" data-pattern="fixed" data-place="6" data-width="200" data-height="200"> <div id="igiokeaw4ag8" class="phx-panel-title clearfix"> <span id="igiokeaw4ag8" class="text pull-left">文章詳情</span> </div> <div id="igiokeaw4ag8" class="phx-panel"> <div id="igiokeaw4ag8" class="appWrapper" id="app_24330443" role="draggable" data-type="app" data-appid="datumInfo" data-config="" data-state="true"> <div id="igiokeaw4ag8" class="appMask"></div> <div id="igiokeaw4ag8" class="appContent"> <div id="igiokeaw4ag8" class="datum_info"> <h1 class="title">化瘀軟堅(jiān)湯聯(lián)合替諾福韋**慢性乙肝肝纖維化63例</h1> <div id="igiokeaw4ag8" class="bgcolor_01"> <div id="igiokeaw4ag8" class="bgcolor_sum"> <div id="igiokeaw4ag8" class="left">日期：2024-11-22 01:49</div> <div id="igiokeaw4ag8" class="right">瀏覽次數(shù)：1069</div> </div> <div id="igiokeaw4ag8" class="bgcolor_sum01"> 摘要：化瘀軟堅(jiān)湯聯(lián)合替諾福韋**慢性乙肝肝纖維化63例探討化瘀軟堅(jiān)湯聯(lián)合替諾福韋對慢性乙肝患者血清肝纖維化的影響,明確其應(yīng)用價(jià)值。方法采用前瞻性研究方案,將126例慢性乙型肝炎肝纖維化患者隨機(jī)分為兩組,對照組63例采用替諾福韋進(jìn)行**,觀察組63例采用軟堅(jiān)化瘀湯聯(lián)合替諾福韋進(jìn)行**,**周期均為48周;觀察患者**后HBV-DNA轉(zhuǎn)陰率,并于**前后抽取患者空腹靜脈血,采用全自動生化分析儀和ELISA試劑盒 </div> </div> <div id="igiokeaw4ag8" class="content"> <p> <span style="color:#231815;font-family:"Microsoft Yahei";font-size:24px;text-align:center;white-space:normal;">化瘀軟堅(jiān)湯聯(lián)合替諾福韋**慢性乙肝肝纖維化63例</span> </p> <p> <span style="color:#231815;font-family:"Microsoft Yahei";font-size:24px;text-align:center;white-space:normal;"><span style="color:#333333;font-family:"Microsoft Yahei";font-size:16px;text-align:justify;white-space:normal;">目的探討化瘀軟堅(jiān)湯聯(lián)合替諾福韋對慢性乙肝患者血清肝纖維化的影響,明確其應(yīng)用價(jià)值。方法采用前瞻性研究方案,將126例慢性乙型肝炎肝纖維化患者隨機(jī)分為兩組,對照組63例采用替諾福韋進(jìn)行**,觀察組63例采用軟堅(jiān)化瘀湯聯(lián)合替諾福韋進(jìn)行**,**周期均為48周;觀察患者**后HBV-DNA轉(zhuǎn)陰率,并于**前后抽取患者空腹靜脈血,采用全自動生化分析儀和ELISA試劑盒檢測肝功能指標(biāo)谷丙轉(zhuǎn)氨酶(alanine aminotransferase,ALT)、谷草轉(zhuǎn)氨酶(aspartate aminotransferase,AST)、總膽紅素(total bilirubin,TBIL)和肝纖維化指標(biāo)透明質(zhì)酸酶(hyalurouidase,HA)、Ⅲ型前膠原(precollagenⅢpeptide,PCⅢ)、Ⅳ型膠原(collagen IV,IVC)及層黏連蛋白(lauinin,LN)。結(jié)果**前,兩組患者的肝功能和肝纖維化水平差異無統(tǒng)計(jì)學(xué)意義(P>0.05);**后,兩組患者的血清ALT、AST、TBIL、HV、PCⅢ、IVC及LN水平均有明顯降低,且觀察組低于對照組,組內(nèi)與組間差異均有統(tǒng)計(jì)學(xué)意義(P<0.05)。另外,觀察組HBV-DNA轉(zhuǎn)陰率為90.4%(57/63),明顯高于對照組的76.2%(48/63),差異有統(tǒng)計(jì)學(xué)意義(P<0.05)。結(jié)論化瘀軟堅(jiān)湯對抑制肝纖維化、改善肝功能有正向作用,聯(lián)合替諾福韋**慢性乙型肝炎可增強(qiáng)療效,具有一定的臨床推廣價(jià)值。</span><br> </span> </p> </div> <div id="igiokeaw4ag8" class="datumrelate"> <span>下一篇：</span> <a 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